Cystic fibrosis is a multisystem disorder that commonly presents with Polycystic Liver Disease symptoms. The liver is characterized by multiple functional units that are composed of an organ and a tube. Cystic fibrosis impairs the function of the organ. Several factors including genetic background, environmental exposure, and inflammation can cause polycystic liver disease symptoms.
What is Polycystic Liver Disease
The polycystic liver disease mainly causes serious liver complications due to hepatotoxicity. Hepatitis causes damage to the liver cells and prevents their productive cycle. Autosomal recessive polycystic liver disease (ARPD) causes the genetic basis for this condition to be transmitted via an autosomal recessive inheritance. A liver X-linked gene is the only gene affected. Genetic counseling is essential for patients suspected of having polycystic liver disease. Inherited genetic bases for polycystic liver disease symptoms in both patients and relatives can be determined through biopsy.
The common pathogenesis of a polycystic liver disease is biliary tree obstruction. The biliary tree obstruction can occur either due to excessive accumulation of bilirubin in the bile duct or due to obstruction of the lymphatic duct. The obstruction causes reduced flow of blood and increases abdominal pressure, resulting in severe inflammation and potential damage to the organ.
Symptoms of Polycystic Liver Disease
Patients with polycystic liver disease symptoms may be diagnosed as having steatosis when there are no symptoms in the liver. When the gallbladder, pancreas, or liver are affected by polycystic liver disease, patients are diagnosed as having polycystic liver disease with symptoms of congestive heart failure. Advanced stages of the disease often involve the formation of large cysts that are capable of causing serious damage to the organ.
In patients who do not have polycystic liver disease, fluid retention, and ascites can occur. Blood bilirubin, protein, cholesterol, albumin, and sodium are the main products of the cellular fluid. Increased cellular fluid, protein, and cholesterol levels are a common consequence of polycystic liver disease, which can affect the liver’s ability to eliminate toxins from the body and produce important substances that are used for cellular metabolism. Increased salt levels in the bloodstream can also result in sodium deficiency.
Liver enlargement and inflammation are some of the common manifestations of polycystic liver disease. Treatment for patients suffering from severe symptoms of polycystic liver disease usually includes fluid restriction and antibiotics. As a chronic condition, patients suffering from polycystic liver disease may require outpatient dialysis therapy to sustain normal kidney function. Acetaminophen, aspirin, sorbitol, and other non-steroidal anti-inflammatory agents may be prescribed to control symptoms of cysts.